Established less than 3 years ago, Jinan Microecological Biomedicine Shandong Laboratory has become the new ‘top stream’.
Source: Popular Daily
Professor Li Xinguang, deputy director of the laboratory, and researcher Chen Jingjing of the Cellular and Neurological Function Testing Platform have made new progress in the field of protein folding; researcher Wang Hangxiang's team has published a review article on nanobiotechnology to help transplanted organs resist rejection in the journal Transplantation; academician Gu Xiaosong and professor Jiang Chunping have published an important paper in the latest issue of Trends in Molecular Medicine. The latest Trends in Molecular Medicine ...... is the official website of Jinan Microecological Biomedicine Shandong Laboratory(hereinafter referred to as the ‘Jinan Laboratory’), and more than ten latest academic achievements come to your eyes.
This is part of the fruitful scientific research results of Jinan Laboratory. As a laboratory established less than three years ago, what is the ‘secret sauce’?
This is a new ‘top stream’ laboratory
‘The laboratory is one of the first six provincial laboratories built in Shandong Province, and is the only new research and development institution focusing on human microecology research in China, which was registered on 13 August 2021.’ Prof Wu Nanping, Executive Deputy Director of the Jinan laboratory, introduced.
The laboratory integrates the advantageous resources of Zhejiang University, Nanjing University, Shandong University, Shandong First Medical University, and establishes strategic cooperative relationships with many domestic well-known pharmaceutical manufacturers, with the purpose of ‘domestic leading, irreplaceable, world-class, and leading the development’, and with the major strategic needs of the country and the world's scientific and technological frontier as the traction, focusing on the ‘microecology biomedicine’. Microecology biomedicine’ in the field of national science and technology innovation strategic needs and biomedicine international power of strategic science and technology frontiers, benchmarking international advanced laboratories, focusing on the construction of “microecology and disease”, “microecology and health and aging” and “microecology and health and aging”, “microecology and health” and “microecology and aging”. The laboratory focuses on three strategic research directions: ‘Microecology and Disease’, ‘Microecology and Health and Aging’ and ‘Microecology Technology and Product Transformation’.
The positioning of the laboratory is unusual, and the team members are all ‘big names’ in the industry. Ms Li Lanjuan, an academician of the Chinese Academy of Engineering, is the director and legal representative of the laboratory. Up to now, more than 100 talents of various types have been introduced and reserved, including 6 academicians, 6 national talents such as Jieqing and Youqing, and 19 provincial talents such as Taishan Scholars.
The main building of the laboratory is located in the 7# building of the first phase of Jinan International Medical Centre Medical Science and Technology Innovation Industrial Park, which is expected to be delivered at the end of June 2024. In addition, a total of about 3,000 square metres of large instrument platforms, animal houses and about 5,000 square metres of GMP pilot bases are also planned and constructed in the second phase of the industrial park, which is expected to be delivered in 2025.
Nowadays, in the Huaiyin District, the Medical Center, the main body of the project under the three-dimensional linkage, the laboratory where the Jinan International Medical Center has three national platforms, three high-end industrial parks, two universities, and more than 30 colleges, hospitals and scientific research institutions and a large number of scientific research talents gathered, high-capacity science and technology innovation platform has become a ‘melting pot’ of talent convergence, The high-capacity science and innovation platform has become a ‘melting pot’ for talents and a ‘strong engine’ for scientific and technological innovation.
Human microecology is closely related to health, disease and aging.
More and more studies show that human health is closely related to microecology.
‘Human micro-ecology is equivalent to ‘organs’ with important roles.’ Wu Nanping said, there are a large number of human body and complex structure of the microbial community, the total weight of about 1.5 kg, equivalent to the weight of the human liver, these colonies constitute the human micro-ecosystem, the number of genes encoded in the system can be up to the human body's own number of genes 150 times, equivalent to the human body's ‘second genome’.
The human micro-ecosystem to maintain balance, is one of the important guarantee of human health. If there is an imbalance in the micro-ecological flora, it may cause sub-health or disease. ‘For example, autism, there have been studies showing that its pathogenesis, healing mechanism and the regulation of intestinal flora have an important relationship.’ Wu Nanping said.
In terms of disease healing, the laboratory studies new anti-infection strategies from the perspective of human microecological balance, focusing on the balance of the flora, reducing the emergence of super-resistant bacteria, protecting organ function, and enhancing the healing effect.
Product development and application of market prospects, ‘micro’ unlimited power!
Only when the scientific research results go out of the laboratory to the enterprise production line, can it really become a ‘panacea’ to help industrial development.
Micro-ecological preparations belong to the strategic emerging industries supported by the national policy, micro-ecological preparations products and technologies will be the focus of vigorous promotion. Currently, micro-ecological preparations have been applied in many fields such as medicine, feed, agriculture and food. Data show that the average annual growth rate of China's microecological preparation market is about 15%.
At present, the laboratory has stocked more than 10 ready-to-transform results, including: microecological probiotic preparations, intestinal microecology detection reagents, hydrogel antibacterial haemostatic materials, and so on. In the next step, the laboratory will widely carry out cutting-edge scientific exploration, training of innovative talents, construction of public scientific research platforms, transformation of scientific and technological achievements, to create a training base for innovative talents, a new source of high-tech and a new engine for incubation of achievements, and to build a micro-ecological biomedical field from the ‘innovation of basic theories’, ‘breakthroughs in key technologies’, ‘breakthroughs in industrialisation’ to ‘breakthroughs in industrialisation’. breakthroughs’, “industrialisation” and “application” in the field of microecology and biomedicine, forming an internationally advanced “research-transformation-application” model, and promoting the development of Micro-ecological biomedical industry, academia, research and application of high-quality development, and strive to create a micro-ecological whole industry closed-loop chain as the characteristics of Jinan (Huaiyin) ‘micro-ecological valley’, contributing to the high-quality development of the regional economy, and providing inexhaustible scientific and technological kinetic energy for the development of Shandong Province and even the country's biomedicine and micro-ecological industry.
At present, Huayin District anchored in the ‘science and innovation to develop the district’ overall goal, set up by the Secretary of the district party committee commander-in-chief of the ‘science and innovation to develop’ leading group, and vigorously promote scientific and technological innovation five-year action plan, relying on the Jinan International Medical Centre, Jinan Huayin Economic Development Zone, Shandong Science and Technology Innovation Base, Shandong digital financial industrial park, ignite science and technology innovation ‘strong engine’, activate high-quality development of a pool of spring water, the dominant industries into a peak, the new quality of productivity is accelerating the formation.
(Reporter Wang Jian, correspondent Cai Chao, Mass Daily - Mass News Client)
