On 3 November 2024, the three-day conference of the Microecology Branch of the Chinese Society of Preventive Medicine 2024 came to a successful conclusion in Jinan, Shandong Province, China. Organised by the Microecology Branch of the Chinese Preventive Medical Association and hosted by Jinan Microecological Biomedicine Shandong Laboratory, this conference is one of the highest level academic conferences in the field of microecology in China. The conference invited more than 50 top experts, scholars and researchers from microecology, biology and other fields at home and abroad, such as academician Li Lanjuan, academician Chen Zijiang, academician Zheng Shusen, academician Yu Jun, etc., to discuss the latest research results, technological advances and future development trends of microecology.
Li Lanjuan, academician of the Chinese Academy of Engineering and director of Jinan Microecological Biomedicine Shandong Laboratory, delivered an enthusiastic speech at the opening ceremony. Academician Li Lanjuan pointed out that research in the field of microecology is not only the key to human health and disease prevention and control, but also an indispensable part of today's rapid development of science and technology, and we need to continue to strengthen the basic research and clinical applications in the field of microecology, and to promote the progress of microecological science. She emphasised that the conference was held to provide a platform for experts and scholars in the field of microecology to exchange and cooperate, share the latest research results and experiences, and contribute to the development of microecological science. Meanwhile, Academician Li expressed her warm welcome to all the guests and looked forward to the success of the congress.
Speech by Li Lanjuan, Academician of the Chinese Academy of Engineering, Director of Jinan Microecological Biomedicine Shandong Laboratory, and Chairman of the Conference
Liu Jingtao, Deputy Secretary of Jinan Huayin District Committee and District Mayor, said in his speech that research in the field of micro-ecology is a hot spot at the forefront of life sciences today, and is of great strategic significance in promoting the development of the biomedical industry. Huayin District has always attached great importance to scientific and technological innovation and the development of biomedical industry, and actively introduced and cultivated high-end talents and innovative enterprises. He said that Huayin District will take this conference as an opportunity to further strengthen cooperation with experts, scholars and enterprises in the field of microecology at home and abroad, and jointly draw a blueprint for the innovative development of microecological biomedical industry chain, so as to make greater contributions to the development of the regional economy and the health and welfare of the people.
Speech by Liu Jingtao, Deputy Secretary of Jinan Huaiyin District Committee and Mayor of Jinan City
Ji Yuan, a municipal cadre of Jinan Science and Technology Bureau, emphasised in his speech that scientific and technological innovation is the core driving force for economic and social development. Jinan Science and Technology Bureau has always attached great importance to scientific and technological innovation in the field of microecology, and actively support relevant enterprises and research institutions to carry out technological research and development and transformation of achievements. Jiyuan said that the organisation of this conference will provide new opportunities and impetus for scientific and technological innovation in the field of microecology in Jinan, and the Municipal Bureau of Science and Technology will continue to increase its support for the field of microecology, promote the cooperation between industry, academia and research, and promote the transformation of scientific and technological achievements, so as to inject new vitality into the economic and social development of Jinan City.
Speech by Ji Yuan, Municipal Cadre of Jinan Municipal Bureau of Science and Technology
Wang Zhongwei, second-level inspector of Shandong Provincial Department of Science and Technology, pointed out in his speech that Shandong Province has always attached great importance to scientific and technological innovation and the development of the biomedical industry in the field of micro-ecology, and actively promoted the research and application of micro-ecology. Wang Zhongwei said that the organisation of this conference is of great significance to strengthen the communication and cooperation between Shandong Province and domestic and foreign microecology fields, and to enhance the academic status and influence of Shandong Province in the field of microecology. He hoped that this conference could further promote scientific and technological innovation and achievement transformation in the field of microecology, and make greater contribution to the economic and social development and people's health in Shandong Province.
Speech by Wang Zhongwei, Second Class Inspector of Shandong Provincial Science and Technology Department
At the forum of academicians and experts, Academician Li Lanjuan made an academic report entitled ‘Chronic Liver Disease and the Regulation of Intestinal Microecology’. Academician Li elaborated the specific mechanism of intestinal microecology in the process of occurrence and development of chronic liver disease, and highlighted the treatment strategy of chronic liver disease based on intestinal microecology regulation. She pointed out that by regulating the intestinal microecological balance, not only can the clinical symptoms of chronic liver disease patients be improved, but also can effectively delay the disease progression and improve the quality of life of patients, and put forward a series of innovative therapeutic methods and technological means, including probiotics, antibiotics, faecal bacteria transplantation, bacterial metabolite inhibitors, TLR inhibitors and so on. In addition, Academician Li Lanjuan also elaborated on the research progress of new generation probiotics, including the advantages, mechanism of action, development process, quality assessment and application potential of new generation probiotics, and made an outlook on the future application of specific flora to make precise intervention in the prevention and treatment of chronic liver disease, revealing for the attendees the potential value of intestinal micro-ecology in the diagnosis, treatment, and prognostic assessment of chronic liver disease.
Academician Li Lanjuan gave a lecture entitled ‘Chronic Liver Disease and the Regulation of Intestinal Microecology’.
Academician Zheng Shusen, on the other hand, brought an academic feast of ‘Liver Transplantation and Microecology in Hepatocellular Carcinoma’ in online format. Academician Zheng elaborated on the study of intratumoural microbiota in hepatocellular carcinoma, the characteristics of intestinal microecology in early-stage hepatocellular carcinoma, the progress of intestinal flora involved in the evolution of hepatocellular carcinoma, pointing out that non-invasive diagnosis of early-stage hepatocellular carcinoma can be made on the basis of intestinal microecology as well as the therapeutic strategies of liver transplantation for hepatocellular carcinoma based on the regulation of microecology, including rational use of microecological modifiers such as probiotic bacteria and probiotic elements, and adoption of fecal colony transplantation and other cutting-edge technologies. These strategies have opened up a brand new vision and path for the clinical practice of liver transplantation for hepatocellular carcinoma, and brought new hope to the majority of patients.
Academician Zheng Shusen gave a lecture entitled ‘Liver transplantation for hepatocellular carcinoma and microecology’.
Academician Chen Zijiang also presented a lecture entitled ‘Intestinal Microecology and Polycystic Ovary Syndrome’ in the same online format also in the same online format. Academician Chen Zijiang discussed in depth the role of intestinal microecology in the pathogenesis of PCOS (Polycystic Ovary Syndrome) through a series of cutting-edge research results and clinical cases. She found that there are significant specific changes in the intestinal microecology of PCOS patients, including a decrease in certain beneficial bacteria and an increase in harmful bacteria. These changes not only affect the physiological function of the gut, but also the reproductive endocrine system in women. Based on these findings, Academician Chen proposed a PCOS treatment strategy based on microecological regulation. She pointed out that by regulating the intestinal microecological balance, not only can the clinical symptoms of PCOS patients be improved, but also may have a positive impact on their reproductive endocrine system. To this end, she shared a series of innovative therapeutic approaches and technological tools, including probiotic interventions, dietary modifications and lifestyle changes, which provide new horizons and pathways for the clinical treatment of PCOS.
Academician Chen Zijiang gave a lecture entitled ‘Intestinal Microecology and Polycystic Ovary Syndrome’.
Prof Wu Nanping, Executive Deputy Director of the Laboratory, Prof Li Xinguang, Prof Xiao Yonghong and Prof Jiang Chunping, Deputy Directors, and Prof Zhu Baoli, PI, and other experts also gave academic reports. They shared the latest research results and cutting-edge technologies around the research progress of microecology in the fields of neurological diseases, immunological diseases, infectious diseases, microecology and metabolic diseases. These presentations not only demonstrated the remarkable achievements of China in the field of microecology, but also promoted the deep integration and synergistic development between academia and industry.
Professor Wu Nanping gave a lecture entitled ‘Research on the intestinal flora of HIV-1 infected patients and its role in the development of Alzheimer's disease’.
Prof Li Xinguang gave a lecture entitled ‘Study on the Mechanism of Gastrointestinal Vagus Nerve Neurocircuitry Regulating Sleep/Wakefulness’.
Professor Xiao Yonghong gave a lecture entitled ‘Microbiome and Drug Resistance’.
Professor Jiang Chunping gave a lecture entitled ‘Living Tumour-Lytic Microorganisms: A New Generation of Pan-Cancer Immunotherapeutic Drugs’.
Professor Baoli Zhu gave a lecture entitled ‘Microbial Pangenome and Human Microbiome Analysis Methods’.
The successful holding of this conference not only demonstrated the remarkable achievements in the field of microecology in China, but also promoted the communication and cooperation between microbiology biomedical academia and industry. Participating experts have expressed that they will take this conference as an opportunity to continue to deepen microecology research, promote scientific and technological innovation and transformation of results, and contribute wisdom and strength to the health and sustainable development of mankind.
